Wayne Macfadden, MD, a former Assistant Professor of Psychiatry and experienced Neuroscience researcher, brings over 30 years of combined experience to the medical field. As a Psychiatrist, Wayne Macfadden, MD, previously focused on substance use disorders such as those involving alcohol and their treatment. Moreover, he has contributed to research on bipolar depression and schizophrenia through various publications.
Bipolar disorder is a mental state characterized by severe mood swings, sleep disturbances, and racing thoughts. Genetic factors strongly contribute to the development of bipolar disorder, particularly from close family members. Biological elements, including brain structure and function in mood-regulating areas like the frontal lobes, may also influence the condition. Moreover, substance use, especially alcohol, raises the risk of developing the condition. Research has revealed that frequent alcohol use may physically аlter the brain, disrupting brain chemicals including neurotransmitters, which transmit signals in the brain. These brain changes can trigger mood episodes in people with bipolar disorder and worsen manic and depressive episodes. Moreover, alcohol use changes the brain’s reward system, making drinking more gratifying and causing individuals to seek it more for pleasure. This heightened response can be especially challenging for individuals with bipolar disorder, as it can worsen impulsive behaviors and mood swings, making their condition more complex and difficult to treat.
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AuthorWayne Macfadden MD: Expert in both Clinical and Research Psychiatry. Archives
March 2024
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